VPN Tracker is the leading Mac VPN client and compatible with almost all IPSec VPN gateways (Try VPN Tracker for free). Please refer to the following table to find out if the VPN Tracker team has already successfully tested VPN Tracker with your TP-Link VPN gateway. If configuration guides are available for your TP-Link VPN gateway, you'll find them here.
In case your TP-Link IPSec VPN gateway is not in the list, there's a good chance that your TP-Link VPN appliance will still work with VPN Tracker. The VPN Tracker manual has general configuration instructions.